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Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

The BubR1/Bub3 complex is an important regulator of chromosome segregation as it facilitates proper kinetochore–microtubule interactions and is also an essential component of the spindle assembly checkpoint (SAC). Whether BubR1/Bub3 localization to kinetochores in human cells stimulates SAC signalli...

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Pubblicato in:Nat Commun
Autori principali: Zhang, Gang, Mendez, Blanca Lopez, Sedgwick, Garry G., Nilsson, Jakob
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963475/
https://ncbi.nlm.nih.gov/pubmed/27457023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12256
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