Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation

Fidelity of chromosome segregation relies on coordination of chromosome biorientation and the spindle checkpoint. Central to this is the kinetochore scaffold KNL1 that integrates the functions of various mitotic regulators including BUB1 and BUBR1. We show that KNL1 contains an extensive array of sh...

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Hauptverfasser: Vleugel, Mathijs, Tromer, Eelco, Omerzu, Manja, Groenewold, Vincent, Nijenhuis, Wilco, Snel, Berend, Kops, Geert J.P.L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2013
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871444/
https://ncbi.nlm.nih.gov/pubmed/24344183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307016
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