A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

The mitotic checkpoint ensures correct chromosome segregation by delaying cell cycle progression until all kinetochores have attached to the mitotic spindle. In this paper, we show that the mitotic checkpoint kinase MPS1 contains an N-terminal localization module, organized in an N-terminal extensio...

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Detalhes bibliográficos
Main Authors: Nijenhuis, Wilco, von Castelmur, Eleonore, Littler, Dene, De Marco, Valeria, Tromer, Eelco, Vleugel, Mathijs, van Osch, Maria H.J., Snel, Berend, Perrakis, Anastassis, Kops, Geert J.P.L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628519/
https://ncbi.nlm.nih.gov/pubmed/23569217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210033
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