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CENP-C Is Involved in Chromosome Segregation, Mitotic Checkpoint Function, and Kinetochore Assembly

CENP-C is a conserved inner kinetochore component. To understand the precise roles of CENP-C in the kinetochore, we created a cell line with a conditional knockout of CENP-C with the tetracycline-inducible system in which the target protein is inactivated at the level of transcription. We found that...

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Autori principali: Kwon, Mi-Sun, Hori, Tetsuya, Okada, Masahiro, Fukagawa, Tatsuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877116/
https://ncbi.nlm.nih.gov/pubmed/17392512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-01-0045
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