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The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly
CENP-A acts as an important epigenetic marker for kinetochore specification. However, the mechanisms by which CENP-A is incorporated into centromeres and the structural basis for kinetochore formation downstream of CENP-A remain unclear. Here, we used a unique chromosome-engineering system in which...
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| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3542802/ https://ncbi.nlm.nih.gov/pubmed/23277427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210106 |
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