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The CCAN recruits CENP-A to the centromere and forms the structural core for kinetochore assembly

CENP-A acts as an important epigenetic marker for kinetochore specification. However, the mechanisms by which CENP-A is incorporated into centromeres and the structural basis for kinetochore formation downstream of CENP-A remain unclear. Here, we used a unique chromosome-engineering system in which...

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Bibliografiske detaljer
Main Authors: Hori, Tetsuya, Shang, Wei-Hao, Takeuchi, Kozo, Fukagawa, Tatsuo
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3542802/
https://ncbi.nlm.nih.gov/pubmed/23277427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201210106
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