FunTree: advances in a resource for exploring and contextualising protein function evolution

Por Sillitoe, Ian, Furnham, Nicholas
Publicado no Nucleic Acids Res (2016)

Model-building strategies for low-resolution X-ray crystallographic data

Por Karmali, Anjum M., Blundell, Tom L., Furnham, Nicholas
Publicado em 2009

Structural basis for inhibition of homologous recombination by the RecX protein

Por Ragone, Stefania, Maman, Joseph D, Furnham, Nicholas, Pellegrini, Luca
Publicado em 2008

Exploring the Biological and Chemical Complexity of the Ligases

Por Holliday, Gemma L., Rahman, Syed Asad, Furnham, Nicholas, Thornton, Janet M.
Publicado em 2014

The Classification and Evolution of Enzyme Function

Por Martínez Cuesta, Sergio, Rahman, Syed Asad, Furnham, Nicholas, Thornton, Janet M.
Publicado no Biophys J (2015)

The evolution of enzyme function in the isomerases

Por Martinez Cuesta, Sergio, Furnham, Nicholas, Rahman, Syed Asad, Sillitoe, Ian, Thornton, Janet M
Publicado em 2014

Comparative modelling by restraint-based conformational sampling

Por Furnham, Nicholas, de Bakker, Paul IW, Gore, Swanand, Burke, David F, Blundell, Tom L
Publicado em 2008

EC-BLAST: A Tool to Automatically Search and Compare Enzyme Reactions

Por Rahman, Syed Asad, Cuesta, Sergio Martinez, Furnham, Nicholas, Holliday, Gemma L., Thornton, Janet M.
Publicado em 2014

Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies

Por Furnham, Nicholas, Dawson, Natalie L., Rahman, Syed A., Thornton, Janet M., Orengo, Christine A.
Publicado no J Mol Biol (2016)

Chopping and Changing: the Evolution of the Flavin-dependent Monooxygenases

Por Mascotti, Maria Laura, Juri Ayub, Maximiliano, Furnham, Nicholas, Thornton, Janet M., Laskowski, Roman A.
Publicado no J Mol Biol (2016)

Exploring the Evolution of Novel Enzyme Functions within Structurally Defined Protein Superfamilies

Por Furnham, Nicholas, Sillitoe, Ian, Holliday, Gemma L., Cuff, Alison L., Laskowski, Roman A., Orengo, Christine A., Thornton, Janet M.
Publicado em 2012

Assembly and Channel Opening in a Bacterial Drug Efflux Machine

Por Bavro, Vassiliy N., Pietras, Zbigniew, Furnham, Nicholas, Pérez-Cano, Laura, Fernández-Recio, Juan, Pei, Xue Yuan, Misra, Rajeev, Luisi, Ben
Publicado em 2008

The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes

Por Furnham, Nicholas, Holliday, Gemma L., de Beer, Tjaart A. P., Jacobsen, Julius O. B., Pearson, William R., Thornton, Janet M.
Publicado em 2014

FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies

Por Furnham, Nicholas, Sillitoe, Ian, Holliday, Gemma L., Cuff, Alison L., Rahman, Syed A., Laskowski, Roman A., Orengo, Christine A., Thornton, Janet M.
Publicado em 2012

Comparisons of Allergenic and Metazoan Parasite Proteins: Allergy the Price of Immunity

Por Tyagi, Nidhi, Farnell, Edward J, Fitzsimmons, Colin M, Ryan, Stephanie, Tukahebwa, Edridah, Maizels, Rick M, Dunne, David W, Thornton, Janet M, Furnham, Nicholas
Publicado no PLoS Comput Biol (2015)

Extending CATH: increasing coverage of the protein structure universe and linking structure with function

Por Cuff, Alison L., Sillitoe, Ian, Lewis, Tony, Clegg, Andrew B., Rentzsch, Robert, Furnham, Nicholas, Pellegrini-Calace, Marialuisa, Jones, David, Thornton, Janet, Orengo, Christine A.
Publicado em 2011

Known Allergen Structures Predict Schistosoma mansoni IgE-Binding Antigens in Human Infection

Por Farnell, Edward J., Tyagi, Nidhi, Ryan, Stephanie, Chalmers, Iain W., Pinot de Moira, Angela, Jones, Frances M., Wawrzyniak, Jakub, Fitzsimmons, Colin M., Tukahebwa, Edridah M., Furnham, Nicholas, Maizels, Rick M., Dunne, David W.
Publicado no Front Immunol (2015)

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

Por Sillitoe, Ian, Cuff, Alison L., Dessailly, Benoit H., Dawson, Natalie L., Furnham, Nicholas, Lee, David, Lees, Jonathan G., Lewis, Tony E., Studer, Romain A., Rentzsch, Robert, Yeats, Corin, Thornton, Janet M., Orengo, Christine A.
Publicado em 2013

CATH: comprehensive structural and functional annotations for genome sequences

Por Sillitoe, Ian, Lewis, Tony E., Cuff, Alison, Das, Sayoni, Ashford, Paul, Dawson, Natalie L., Furnham, Nicholas, Laskowski, Roman A., Lee, David, Lees, Jonathan G., Lehtinen, Sonja, Studer, Romain A., Thornton, Janet, Orengo, Christine A.
Publicado no Nucleic Acids Res (2014)

QSAR-Driven Discovery of Novel Chemical Scaffolds Active Against Schistosoma mansoni

Por Melo-Filho, Cleber C., Dantas, Rafael F., Braga, Rodolpho C., Neves, Bruno J., Senger, Mario R., Valente, Walter C.G., Rezende-Neto, João M., Chaves, Willian T., Muratov, Eugene N., Paveley, Ross A., Furnham, Nicholas, Kamentsky, Lee, Carpenter, Anne E., Silva-Junior, Floriano P., Andrade, Carolina H.
Publicado no J Chem Inf Model (2016)