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Prediction of impacts of mutations on protein structure and interactions: SDM, a statistical approach, and mCSM, using machine learning

Next‐generation sequencing methods have not only allowed an understanding of genome sequence variation during the evolution of organisms but have also provided invaluable information about genetic variants in inherited disease and the emergence of resistance to drugs in cancers and infectious diseas...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Pandurangan, Arun Prasad, Blundell, Tom L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933854/
https://ncbi.nlm.nih.gov/pubmed/31693276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3774
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