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mCSM: predicting the effects of mutations in proteins using graph-based signatures

Motivation: Mutations play fundamental roles in evolution by introducing diversity into genomes. Missense mutations in structural genes may become either selectively advantageous or disadvantageous to the organism by affecting protein stability and/or interfering with interactions between partners....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pires, Douglas E. V., Ascher, David B., Blundell, Tom L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904523/
https://ncbi.nlm.nih.gov/pubmed/24281696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt691
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