mCSM-AB: a web server for predicting antibody–antigen affinity changes upon mutation with graph-based signatures

por Pires, Douglas E.V., Ascher, David B.
Publicado no Nucleic Acids Res (2016)

CSM-lig: a web server for assessing and comparing protein–small molecule affinities

por Pires, Douglas E.V., Ascher, David B.
Publicado no Nucleic Acids Res (2016)

mCSM–NA: predicting the effects of mutations on protein–nucleic acids interactions

por Pires, Douglas E.V., Ascher, David B.
Publicado no Nucleic Acids Res (2017)

mmCSM-AB: guiding rational antibody engineering through multiple point mutations

por Myung, Yoochan, Pires, Douglas E V, Ascher, David B
Publicado no Nucleic Acids Res (2020)

mCSM: predicting the effects of mutations in proteins using graph-based signatures

por Pires, Douglas E. V., Ascher, David B., Blundell, Tom L.
Publicado em 2014

DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach

por Pires, Douglas E.V., Ascher, David B., Blundell, Tom L.
Publicado em 2014

Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes

por Pires, Douglas E.V., Blundell, Tom L., Ascher, David B.
Publicado no Nucleic Acids Res (2014)

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures

por Pires, Douglas E. V., Blundell, Tom L., Ascher, David B.
Publicado no J Med Chem (2015)

mCSM-lig: quantifying the effects of mutations on protein-small molecule affinity in genetic disease and emergence of drug resistance

por Pires, Douglas E. V., Blundell, Tom L., Ascher, David B.
Publicado no Sci Rep (2016)

dendPoint: a web resource for dendrimer pharmacokinetics investigation and prediction

por Kaminskas, Lisa M., Pires, Douglas E. V., Ascher, David B.
Publicado no Sci Rep (2019)

mCSM-membrane: predicting the effects of mutations on transmembrane proteins

por Pires, Douglas E V, Rodrigues, Carlos H M, Ascher, David B
Publicado no Nucleic Acids Res (2020)

DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations

por Rodrigues, Carlos H.M., Pires, Douglas E.V., Ascher, David B.
Publicado no Protein Sci (2020)

mmCSM-PPI: predicting the effects of multiple point mutations on protein–protein interactions

por Rodrigues, Carlos H M, Pires, Douglas E V, Ascher, David B
Publicado no Nucleic Acids Res (2021)

In silico functional dissection of saturation mutagenesis: Interpreting the relationship between phenotypes and changes in protein stability, interactions and activity

por Pires, Douglas E. V., Chen, Jing, Blundell, Tom L., Ascher, David B.
Publicado no Sci Rep (2016)

mCSM-PPI2: predicting the effects of mutations on protein–protein interactions

por Rodrigues, Carlos H M, Myung, Yoochan, Pires, Douglas E V, Ascher, David B
Publicado no Nucleic Acids Res (2019)

Human LC3 and GABARAP subfamily members achieve functional specificity via specific structural modulations

por Jatana, Nidhi, Ascher, David B., Pires, Douglas E.V., Gokhale, Rajesh S., Thukral, Lipi
Publicado no Autophagy (2019)

GASS-WEB: a web server for identifying enzyme active sites based on genetic algorithms

por Moraes, João P. A., Pappa, Gisele L., Pires, Douglas E. V., Izidoro, Sandro C.
Publicado no Nucleic Acids Res (2017)

pdCSM-cancer: Using Graph-Based Signatures to Identify Small Molecules with Anticancer Properties

por Al-Jarf, Raghad, de Sá, Alex G. C., Pires, Douglas E. V., Ascher, David B.
Publicado no J Chem Inf Model (2021)

Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches

por Portelli, Stephanie, Myung, Yoochan, Furnham, Nicholas, Vedithi, Sundeep Chaitanya, Pires, Douglas E. V., Ascher, David B.
Publicado no Sci Rep (2020)

Distinguishing between PTEN clinical phenotypes through mutation analysis

por Portelli, Stephanie, Barr, Lucy, de Sá, Alex G.C., Pires, Douglas E.V., Ascher, David B.
Publicado no Comput Struct Biotechnol J (2021)