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Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif

BRCA1 BRCT domains function as phosphoprotein-binding modules for recognition of the phosphorylated protein-sequence motif pSXXF. While the motif interaction interface provides strong anchor points for binding, protein regions outside the motif have recently been found to be important for binding af...

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Detalhes bibliográficos
Publicado no:Prog Biophys Mol Biol
Main Authors: Wu, Qian, Jubb, Harry, Blundell, Tom L.
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728184/
https://ncbi.nlm.nih.gov/pubmed/25701377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2015.02.003
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