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Phosphopeptide interactions of the Nbs1 N-terminal FHA-BRCT1/2 domains
Human Nbs1, a component of the MRN complex involved in DNA double strand break repair, contains a concatenated N-terminal FHA-BRCT1/2 sequence that supports interaction with multiple phosphopeptide binding partners. MDC1 binding localizes Nbs1 to the damage site, while binding of CDK-phosphorylated...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8079451/ https://ncbi.nlm.nih.gov/pubmed/33907233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-88400-7 |
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