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Characterization of the APLF FHA–XRCC1 phosphopeptide interaction and its structural and functional implications

Aprataxin and PNKP-like factor (APLF) is a DNA repair factor containing a forkhead-associated (FHA) domain that supports binding to the phosphorylated FHA domain binding motifs (FBMs) in XRCC1 and XRCC4. We have characterized the interaction of the APLF FHA domain with phosphorylated XRCC1 peptides...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Kim, Kyungmin, Pedersen, Lars C., Kirby, Thomas W., DeRose, Eugene F., London, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716189/
https://ncbi.nlm.nih.gov/pubmed/29059378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx941
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