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XRCC4's interaction with XLF is required for coding (but not signal) end joining

XRCC4 and XLF are structurally related proteins important for DNA Ligase IV function. XRCC4 forms a tight complex with DNA Ligase IV while XLF interacts directly with XRCC4. Both XRCC4 and XLF form homodimers that can polymerize as heterotypic filaments independently of DNA Ligase IV. Emerging struc...

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書誌詳細
主要な著者: Roy, Sunetra, Andres, Sara N., Vergnes, Alexandra, Neal, Jessica A., Xu, Yao, Yu, Yaping, Lees-Miller, Susan P., Junop, Murray, Modesti, Mauro, Meek, Katheryn
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287172/
https://ncbi.nlm.nih.gov/pubmed/22228831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1315
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