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Crystal structure of the Xrcc4 DNA repair protein and implications for end joining
XRCC4 is essential for carrying out non-homologous DNA end joining (NHEJ) in all eukaryotes and, in particular, V(D)J recombination in vertebrates. Xrcc4 protein forms a complex with DNA ligase IV that rejoins two DNA ends in the last step of V(D)J recombination and NHEJ to repair double strand brea...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2000
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305814/ https://ncbi.nlm.nih.gov/pubmed/11080143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.22.5962 |
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