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Crystal structure of a SeqA–N filament: implications for DNA replication and chromosome organization

Escherichia coli SeqA binds clusters of transiently hemimethylated GATC sequences and sequesters the origin of replication, oriC, from methylation and premature reinitiation. Besides oriC, SeqA binds and organizes newly synthesized DNA at replication forks. Binding to multiple GATC sites is crucial...

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Sonraí Bibleagrafaíochta
Main Authors: Guarné, Alba, Brendler, Therese, Zhao, Qinghai, Ghirlando, Rodolfo, Austin, Stuart, Yang, Wei
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1142570/
https://ncbi.nlm.nih.gov/pubmed/15933720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600634
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