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Crystal structure of a SeqA–N filament: implications for DNA replication and chromosome organization
Escherichia coli SeqA binds clusters of transiently hemimethylated GATC sequences and sequesters the origin of replication, oriC, from methylation and premature reinitiation. Besides oriC, SeqA binds and organizes newly synthesized DNA at replication forks. Binding to multiple GATC sites is crucial...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1142570/ https://ncbi.nlm.nih.gov/pubmed/15933720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600634 |
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