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Crystallization and preliminary X-ray diffraction analysis of SeqA bound to a pair of hemimethylated GATC sites

Escherichia coli SeqA is a negative regulator of DNA replication. The SeqA protein forms a high-affinity complex with newly replicated DNA at the origin of replication and thus prevents premature re-initiation events. Beyond the origin, SeqA is found at the replication forks, where it organizes newl...

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Bibliografiske detaljer
Main Authors: Chung, Yu Seon, Guarné, Alba
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2496869/
https://ncbi.nlm.nih.gov/pubmed/18540078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108014851
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