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Structural Basis of BACH1 Phosphopeptide Recognition by BRCA1 Tandem BRCT Domains

BRCT tandem domains, found in many proteins involved in DNA damage checkpoint and DNA repair pathways, were recently shown to be phosphopeptide binding motifs. Using solution nuclear magnetic resonance (NMR) spectroscopy and mutational analysis, we have characterized the interaction of BRCA1-BRCT do...

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Detalhes bibliográficos
Main Authors: Botuyan, Maria Victoria E., Nominé, Yves, Yu, Xiaochun, Juranic, Nenad, Macura, Slobodan, Chen, Junjie, Mer, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652423/
https://ncbi.nlm.nih.gov/pubmed/15242590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2004.06.002
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