Molecular Basis for the Association of Human E4B U box Ubiquitin Ligase with E2 Conjugating Enzymes UbcH5c and Ubc4

Human E4B, also called UFD2a, is a U-box-containing protein that functions as an E3 ubiquitin ligase and an E4 polyubiquitin chain elongation factor. E4B is thought to participate in the proteasomal degradation of misfolded or damaged proteins through association with chaperones. The U-box domain is...

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Main Authors: Benirschke, Robert C., Thompson, James R., Nominé, Yves, Wasielewski, Emeric, Juranić, Nenad, Macura, Slobodan, Hatakeyama, Shigetsugu, Nakayama, Keiichi I., Botuyan, Maria Victoria, Mer, Georges
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005147/
https://ncbi.nlm.nih.gov/pubmed/20696396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.04.017
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