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UbcH5 Interacts with Substrates to Participate in Lysine Selection with the E3 Ubiquitin Ligase CHIP

The E3 ubiquitin ligase C-terminus of Hsc70 interacting protein (CHIP) plays a critical role in regulating the ubiquitin-dependent degradation of misfolded proteins. CHIP mediates the ubiquitination of the alpha-amino terminus of substrates with the E2 Ube2w and facilitates the ubiquitination of lys...

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Dades bibliogràfiques
Publicat a:Biochemistry
Autors principals: Kanack, Adam, Vittal, Vinayak, Haver, Holly, Keppel, Theodore, Gundry, Rebekah L., Klevit, Rachel E., Scaglione, Kenneth Matthew
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780428/
https://ncbi.nlm.nih.gov/pubmed/32401531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00084
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