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Tumor suppressor candidate TSSC5 is regulated by UbcH6and a novel ubiquitin ligase RING105

The region of human chromosome 11p15.5 is linked with Beckwith–Wiedemann syndrome that is associated with susceptibility to Wilms’ tumor, rhabdomyosarcoma and hepatoblastoma. TSSC5 (tumor-suppressing subchromosomal transferable fragment cDNA; also known as ORCTL2/IMPT1/BWR1A/SLC22A1L) is located in...

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Detalhes bibliográficos
Main Authors: Yamada, HY, Gorbsky, GJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713668/
https://ncbi.nlm.nih.gov/pubmed/16314844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209167
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