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UbcH5 Interacts with Substrates to Participate in Lysine Selection with the E3 Ubiquitin Ligase CHIP
The E3 ubiquitin ligase C-terminus of Hsc70 interacting protein (CHIP) plays a critical role in regulating the ubiquitin-dependent degradation of misfolded proteins. CHIP mediates the ubiquitination of the alpha-amino terminus of substrates with the E2 Ube2w and facilitates the ubiquitination of lys...
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| Publié dans: | Biochemistry |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7780428/ https://ncbi.nlm.nih.gov/pubmed/32401531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00084 |
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