Structural Basis of BACH1 Phosphopeptide Recognition by BRCA1 Tandem BRCT Domains

BRCT tandem domains, found in many proteins involved in DNA damage checkpoint and DNA repair pathways, were recently shown to be phosphopeptide binding motifs. Using solution nuclear magnetic resonance (NMR) spectroscopy and mutational analysis, we have characterized the interaction of BRCA1-BRCT do...

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Hlavní autoři: Botuyan, Maria Victoria E., Nominé, Yves, Yu, Xiaochun, Juranic, Nenad, Macura, Slobodan, Chen, Junjie, Mer, Georges
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652423/
https://ncbi.nlm.nih.gov/pubmed/15242590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2004.06.002
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