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FAK Structure and Regulation by Membrane Interactions and Force in Focal Adhesions
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase with key roles in the regulation of cell adhesion migration, proliferation and survival. In cancer FAK is a major driver of invasion and metastasis and its upregulation is associated with poor patient prognosis. FAK is autoinhibited in th...
Guardat en:
| Publicat a: | Biomolecules |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7072507/ https://ncbi.nlm.nih.gov/pubmed/31991559 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020179 |
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