A carregar...
Crystal structures of NK1–heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor
NK1 is a splice variant of the polypeptide growth factor HGF/SF, which consists of the N-terminal (N) and first kringle (K) domain and requires heparan sulfate or soluble heparin for activity. We describe two X-ray crystal structures of NK1–heparin complexes that define a heparin-binding site in the...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125671/ https://ncbi.nlm.nih.gov/pubmed/11597998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.20.5543 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|