Crystal Structures of the FAK Kinase in Complex with TAE226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical DFG Conformation

Similar Items

• Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors
  od: McCoull, William, i dr.
  Izdano: (2016)
• TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells.
  od: Hiroki Otani, i dr.
  Izdano: (2015-01-01)
• TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells
  od: Otani, Hiroki, i dr.
  Izdano: (2015)
• Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models
  od: Fukami, Shigemi, i dr.
  Izdano: (2019)
• Different conformational families of pyrimidine.purine.pyrimidine triple helices depending on backbone composition.
  od: Han, H, i dr.
  Izdano: (1994)