Functions of NF-κB1 and NF-κB2 in immune cell biology

by Beinke, Sören, Ley, Steven C.
Published 2004

RNF11, a new piece in the A20 puzzle

by Jacque, Emilie, Ley, Steven C
Published 2009

New insights into NF-κB regulation and function

by Sun, Shao-Cong, Ley, Steven C.
Published in Trends Immunol (2008)

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

by Gantke, Thorsten, Sriskantharajah, Srividya, Ley, Steven C
Published 2011

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

by Gantke, Thorsten, Sriskantharajah, Srividya, Ley, Steven C
Published 2011

TNF activation of NF-κB is essential for development of single-positive thymocytes

by Webb, Louise V., Ley, Steven C., Seddon, Benedict
Published in J Exp Med (2016)

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

by Janes, Peter W., Ley, Steven C., Magee, Anthony I.
Published 1999

NF-κB signaling mediates homeostatic maturation of new T cells

by Silva, Ana, Cornish, Georgina, Ley, Steven C., Seddon, Benedict
Published 2014

ZAP-70 Protein Tyrosine Kinase Is Constitutively Targeted to the T Cell Cortex Independently of its SH2 Domains

by Huby, Russell D.J., Iwashima, Makio, Weiss, Arthur, Ley, Steven C.
Published 1997

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival

by Jacque, Emilie, Schweighoffer, Edina, Tybulewicz, Victor L.J., Ley, Steven C.
Published in J Exp Med (2015)

ABIN1 Protein Cooperates with TAX1BP1 and A20 Proteins to Inhibit Antiviral Signaling

by Gao, Linlin, Coope, Helen, Grant, Susan, Ma, Averil, Ley, Steven C., Harhaj, Edward W.
Published 2011

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells

by Gantke, Thorsten, Boussouf, Sabrina, Janzen, Julia, Morrice, Nicholas A., Howell, Steven, Mühlberger, Elke, Ley, Steven C.
Published 2013

A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation

by Ventura, Sonia, Cano, Florencia, Kannan, Yashaswini, Breyer, Felix, Pattison, Michael J., Wilson, Mark S., Ley, Steven C.
Published in J Exp Med (2018)

CARD14(E138A) signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

by Manils, Joan, Webb, Louise V, Howes, Ashleigh, Janzen, Julia, Boeing, Stefan, Bowcock, Anne M, Ley, Steven C
Published in eLife (2020)

Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes

by Smyth, Lesley A., Williams, Owen, Huby, Russell D. J., Norton, Trisha, Acuto, Oreste, Ley, Steven C., Kioussis, Dimitris
Published 1998

Coordinate Regulation of TPL-2 and NF-κB Signaling in Macrophages by NF-κB1 p105

by Yang, Huei-Ting, Papoutsopoulou, Stamatia, Belich, Monica, Brender, Christine, Janzen, Julia, Gantke, Thorsten, Handley, Matt, Ley, Steven C.
Published 2012

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

by Kannan, Yashaswini, Entwistle, Lewis J., Pelly, Victoria S., Perez-Lloret, Jimena, Walker, Alan W., Ley, Steven C., Wilson, Mark S.
Published in PLoS Pathog (2017)

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation

by Howes, Ashleigh, O’Sullivan, Paul A., Breyer, Felix, Ghose, Ashavari, Cao, Li, Krappmann, Daniel, Bowcock, Anne M., Ley, Steven C.
Published in Biochem J (2016)

IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

by Ben-Addi, Abduelhakem, Mambole-Dema, Agnes, Brender, Christine, Martin, Stephen R., Janzen, Julia, Kjaer, Sven, Smerdon, Stephen J., Ley, Steven C.
Published 2014

IκB Kinase 2 Regulates TPL-2 Activation of Extracellular Signal-Regulated Kinases 1 and 2 by Direct Phosphorylation of TPL-2 Serine 400

by Roget, Karine, Ben-Addi, Abduelhakem, Mambole-Dema, Agnes, Gantke, Thorsten, Yang, Huei-Ting, Janzen, Julia, Morrice, Nick, Abbott, Derek, Ley, Steven C.
Published 2012