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New insights into NF-κB regulation and function
NF-κB (nuclear factor-κB) transcription factors have multiple critical roles in the regulation of immune responses. In unstimulated cells, NF-κB proteins are sequestered in the cytoplasm by IκB inhibitory proteins. Various immune stimuli induce the IκB kinase (IKK) to phosphorylate IκBs, triggering...
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| Publicado no: | Trends Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5751948/ https://ncbi.nlm.nih.gov/pubmed/18775672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2008.07.003 |
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