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Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

The IκB kinase (IKK) complex plays a well-documented role in innate and adaptive immunity. This function has been widely attributed to its role as the central activator of the NF-κB family of transcription factors. However, another important consequence of IKK activation is the regulation of TPL-2,...

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Detalhes bibliográficos
Main Authors: Gantke, Thorsten, Sriskantharajah, Srividya, Ley, Steven C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193413/
https://ncbi.nlm.nih.gov/pubmed/21135874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.173
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