Functions of NF-κB1 and NF-κB2 in immune cell biology

Por Beinke, Sören, Ley, Steven C.
Publicado em 2004

RNF11, a new piece in the A20 puzzle

Por Jacque, Emilie, Ley, Steven C
Publicado em 2009

New insights into NF-κB regulation and function

Por Sun, Shao-Cong, Ley, Steven C.
Publicado no Trends Immunol (2008)

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

Por Gantke, Thorsten, Sriskantharajah, Srividya, Ley, Steven C
Publicado em 2011

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase

Por Gantke, Thorsten, Sriskantharajah, Srividya, Ley, Steven C
Publicado em 2011

TNF activation of NF-κB is essential for development of single-positive thymocytes

Por Webb, Louise V., Ley, Steven C., Seddon, Benedict
Publicado no J Exp Med (2016)

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

Por Janes, Peter W., Ley, Steven C., Magee, Anthony I.
Publicado em 1999

NF-κB signaling mediates homeostatic maturation of new T cells

Por Silva, Ana, Cornish, Georgina, Ley, Steven C., Seddon, Benedict
Publicado em 2014

ZAP-70 Protein Tyrosine Kinase Is Constitutively Targeted to the T Cell Cortex Independently of its SH2 Domains

Por Huby, Russell D.J., Iwashima, Makio, Weiss, Arthur, Ley, Steven C.
Publicado em 1997

BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival

Por Jacque, Emilie, Schweighoffer, Edina, Tybulewicz, Victor L.J., Ley, Steven C.
Publicado no J Exp Med (2015)

ABIN1 Protein Cooperates with TAX1BP1 and A20 Proteins to Inhibit Antiviral Signaling

Por Gao, Linlin, Coope, Helen, Grant, Susan, Ma, Averil, Ley, Steven C., Harhaj, Edward W.
Publicado em 2011

Ebola virus VP35 induces high-level production of recombinant TPL-2–ABIN-2–NF-κB1 p105 complex in co-transfected HEK-293 cells

Por Gantke, Thorsten, Boussouf, Sabrina, Janzen, Julia, Morrice, Nicholas A., Howell, Steven, Mühlberger, Elke, Ley, Steven C.
Publicado em 2013

A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation

Por Ventura, Sonia, Cano, Florencia, Kannan, Yashaswini, Breyer, Felix, Pattison, Michael J., Wilson, Mark S., Ley, Steven C.
Publicado no J Exp Med (2018)

CARD14(E138A) signalling in keratinocytes induces TNF-dependent skin and systemic inflammation

Por Manils, Joan, Webb, Louise V, Howes, Ashleigh, Janzen, Julia, Boeing, Stefan, Bowcock, Anne M, Ley, Steven C
Publicado no eLife (2020)

Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes

Por Smyth, Lesley A., Williams, Owen, Huby, Russell D. J., Norton, Trisha, Acuto, Oreste, Ley, Steven C., Kioussis, Dimitris
Publicado em 1998

Coordinate Regulation of TPL-2 and NF-κB Signaling in Macrophages by NF-κB1 p105

Por Yang, Huei-Ting, Papoutsopoulou, Stamatia, Belich, Monica, Brender, Christine, Janzen, Julia, Gantke, Thorsten, Handley, Matt, Ley, Steven C.
Publicado em 2012

TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus

Por Kannan, Yashaswini, Entwistle, Lewis J., Pelly, Victoria S., Perez-Lloret, Jimena, Walker, Alan W., Ley, Steven C., Wilson, Mark S.
Publicado no PLoS Pathog (2017)

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation

Por Howes, Ashleigh, O’Sullivan, Paul A., Breyer, Felix, Ghose, Ashavari, Cao, Li, Krappmann, Daniel, Bowcock, Anne M., Ley, Steven C.
Publicado no Biochem J (2016)

IκB kinase-induced interaction of TPL-2 kinase with 14-3-3 is essential for Toll-like receptor activation of ERK-1 and -2 MAP kinases

Por Ben-Addi, Abduelhakem, Mambole-Dema, Agnes, Brender, Christine, Martin, Stephen R., Janzen, Julia, Kjaer, Sven, Smerdon, Stephen J., Ley, Steven C.
Publicado em 2014

IκB Kinase 2 Regulates TPL-2 Activation of Extracellular Signal-Regulated Kinases 1 and 2 by Direct Phosphorylation of TPL-2 Serine 400

Por Roget, Karine, Ben-Addi, Abduelhakem, Mambole-Dema, Agnes, Gantke, Thorsten, Yang, Huei-Ting, Janzen, Julia, Morrice, Nick, Abbott, Derek, Ley, Steven C.
Publicado em 2012