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BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival
B cell activating factor (BAFF) stimulation of the BAFF receptor (BAFF-R) is essential for the homeostatic survival of mature B cells. Earlier in vitro experiments with inhibitors that block MEK 1 and 2 suggested that activation of ERK 1 and 2 MAP kinases is required for BAFF-R to promote B cell sur...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451135/ https://ncbi.nlm.nih.gov/pubmed/25987726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142127 |
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