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A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation
TPL-2 MAP 3-kinase promotes inflammation in numerous mouse disease models and is an attractive anti-inflammatory drug target. However, TPL-2–deficient (Map3k8(−/−)) mice develop exacerbated allergic airway inflammation to house dust mite (HDM) compared with wild type controls. Here, we show that Map...
Kaydedildi:
Yayımlandı: | J Exp Med |
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Asıl Yazarlar: | , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Rockefeller University Press
2018
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6219730/ https://ncbi.nlm.nih.gov/pubmed/30337469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20170852 |
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