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NF-κB signaling mediates homeostatic maturation of new T cells

Interleukin (IL)-7 is critical for the maintenance of the peripheral T-cell compartment of the adaptive immune system. IL-7 receptor α ( IL-7Rα) expression is subject to developmental regulation and new T cells induce expression as they leave the thymus, which is essential for their long-term surviv...

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Detalhes bibliográficos
Main Authors: Silva, Ana, Cornish, Georgina, Ley, Steven C., Seddon, Benedict
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948292/
https://ncbi.nlm.nih.gov/pubmed/24550492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319397111
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