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The Toll/NF-κB signaling pathway is required for epidermal wound repair in Drosophila

The Toll/NF-κB pathway, first identified in studies of dorsal-ventral polarity in the early Drosophila embryo, is well known for its role in the innate immune response. Here, we reveal that the Toll/NF-κB pathway is essential for wound closure in late Drosophila embryos. Toll mutants and Dif dorsal...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Carvalho, Lara, Jacinto, António, Matova, Nina
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273363/
https://ncbi.nlm.nih.gov/pubmed/25427801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408224111
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