The roles of fractalkine signaling in neurodegenerative disease

Por Lamb, Bruce
Publicado em 2012

Spatial and temporal control of age-related APP processing in genomic-based β-secretase transgenic mice

Por Chiocco, Matthew J., Lamb, Bruce T.
Publicado em 2006

Genetic loci modulating amyloid-beta levels in a mouse model of Alzheimer's disease

Por Ryman, Davis, Gao, Yuan, Lamb, Bruce T.
Publicado em 2007

Peripheral macrophages not ADept at amyloid clearance

Por Jay, Taylor, Lamb, Bruce, Landreth, Gary
Publicado no J Exp Med (2015)

Right sizing funding for Alzheimer's disease

Por Golde, Todd E, Lamb, Bruce T, Galasko, Douglas
Publicado em 2011

Human tau expression reduces adult neurogenesis in a mouse model of tauopathy

Por Komuro, Yutaro, Xu, Guixiang, Bhaskar, Kiran, Lamb, Bruce T.
Publicado no Neurobiol Aging (2015)

The Cleavage Products of Amyloid-β Precursor Protein Are Sorted to Distinct Carrier Vesicles That Are Independently Transported within Neurites

Por Muresan, Virgil, Varvel, Nicholas H., Lamb, Bruce T., Muresan, Zoia
Publicado em 2009

The PI3K-Akt-mTOR pathway regulates Aβ oligomer induced neuronal cell cycle events

Por Bhaskar, Kiran, Miller, Megan, Chludzinski, Alexandra, Herrup, Karl, Zagorski, Michael, Lamb, Bruce T
Publicado em 2009

Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease

Por Cameron, Brent, Tse, Wayne, Lamb, Raza, Li, Xiaoxia, Lamb, Bruce T., Landreth, Gary E.
Publicado em 2012

Altered Amyloid-β Metabolism and Deposition in Genomic-based β-Secretase Transgenic Mice

Por Chiocco, Matthew J., Kulnane, Laura Shapiro, Younkin, Linda, Younkin, Steve, Evin, Geneviève, Lamb, Bruce T.
Publicado em 2004

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain

Por Ghosal, Kaushik, Vogt, Daniel L., Liang, Man, Shen, Yong, Lamb, Bruce T., Pimplikar, Sanjay W.
Publicado em 2009

The presence of Aβ seeds, and not age per se, is critical to the initiation of Aβ deposition in the brain

Por Hamaguchi, Tsuyoshi, Eisele, Yvonne S., Varvel, Nicholas H., Lamb, Bruce T., Walker, Lary C., Jucker, Mathias
Publicado em 2011

Residues at P2-P1 positions of ε- and ζ-cleavage sites are important in formation of beta-amyloid peptide

Por Tan, Jianxin, Mao, Guozhang, Cui, Mei-Zhen, Lamb, Bruce, Sy, Man-Sun, Xu, Xuemin
Publicado em 2009

Aβ Oligomers Induce Neuronal Cell Cycle Events in Alzheimer's Disease

Por Varvel, Nicholas H., Bhaskar, Kiran, Patil, Anita R., Pimplikar, Sanjay W., Herrup, Karl, Lamb, Bruce T.
Publicado em 2008

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

Por Bhaskar, Kiran, Konerth, Megan, Kokiko-Cochran, Olga N., Cardona, Astrid, Ransohoff, Richard M., Lamb, Bruce T.
Publicado em 2010

The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice

Por Vidal, Ruben, Sammeta, Neeraja, Garringer, Holly J., Sambamurti, Kumar, Miravalle, Leticia, Lamb, Bruce T., Ghetti, Bernardino
Publicado em 2012

Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury

Por Gyoneva, Stefka, Kim, Daniel, Katsumoto, Atsuko, Kokiko-Cochran, O. Nicole, Lamb, Bruce T., Ransohoff, Richard M.
Publicado no J Neuroinflammation (2015)

Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology

Por Maphis, Nicole M., Jiang, Shanya, Binder, Jessica, Wright, Carrie, Gopalan, Banu, Lamb, Bruce T., Bhaskar, Kiran
Publicado no Front Mol Neurosci (2017)

NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease

Por Varvel, Nicholas H., Bhaskar, Kiran, Kounnas, Maria Z., Wagner, Steven L., Yang, Yan, Lamb, Bruce T., Herrup, Karl
Publicado em 2009

CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer’s Disease Mouse Models

Por Lee, Sungho, Varvel, Nicholas H., Konerth, Megan E., Xu, Guixiang, Cardona, Astrid E., Ransohoff, Richard M., Lamb, Bruce T.
Publicado em 2010