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Human tau expression reduces adult neurogenesis in a mouse model of tauopathy

Accumulation of hyperphosphorylated and aggregated microtubule-associated protein tau (MAPT) is a central feature of a class of neurodegenerative diseases termed tauopathies. Notably, there is increasing evidence that tauopathies, including Alzheimer's disease, are also characterized by a reduc...

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Vydáno v:Neurobiol Aging
Hlavní autoři: Komuro, Yutaro, Xu, Guixiang, Bhaskar, Kiran, Lamb, Bruce T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724414/
https://ncbi.nlm.nih.gov/pubmed/25863528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.03.002
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