Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology

Increasing evidence suggests that hyperphosphorylation and aggregation of microtubule-associated protein tau (MAPT or tau) correlates with the development of cognitive impairment in Alzheimer’s disease (AD) and related tauopathies. While numerous attempts have been made to model AD-relevant tau path...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Maphis, Nicole M., Jiang, Shanya, Binder, Jessica, Wright, Carrie, Gopalan, Banu, Lamb, Bruce T., Bhaskar, Kiran
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355442/
https://ncbi.nlm.nih.gov/pubmed/28367114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00069
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