Chargement en cours...
Residues at P2-P1 positions of ε- and ζ-cleavage sites are important in formation of beta-amyloid peptide
Most of the Alzheimer’s disease (AD)-linked mutations in amyloid precursor protein (APP), which cause abnormal production of β-amyloid (Aβ), are localized at the major β-secretase- and γ-secretase cleavage sites. In this study, using an APP-knockout mouse neuronal cell line, our data demonstrated th...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3520095/ https://ncbi.nlm.nih.gov/pubmed/19716417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.08.010 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|