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Distinct negative regulation of the human embryonic globin genes ζ and ε

The human embryonic globin genes ζ and ε are expressed when erythropoiesis is initiated at about the third week of development but are subsequently repressed as expression of the fetal globins, α and γ, begins. We have examined the promoter region of the human ζ-globin and ε-globin genes in order to...

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Pubblicato in:Gene Expr
Autori principali: Watt, Paul, Lamb, Peter, Proudfoot, Nicholas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cognizant Communication Corporation 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081625/
https://ncbi.nlm.nih.gov/pubmed/8508028
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