Pen-2 is dispensable for endoproteolysis of presenilin 1, and nicastrin-Aph subcomplex is important for both γ-secretase assembly and substrate recruitment

Por Mao, Guozhang, Cui, Mei-Zhen, Li, Tong, Jin, Yipeng, Xu, Xuemin
Publicado em 2012

BOTH THE N-TERMINAL FRAGMENT AND THE PROTEIN-PROTEIN INTERACTION DOMAIN (PDZ DOMAIN) ARE REQUIRED FOR THE PRO-APOPTOTIC ACTIVITY OF PRESENILIN-ASSOCIATED PROTEIN PSAP

Por Mao, Guozhang, Tan, Jianxin, Shi, Yongchang, Cui, Mei-Zhen, Xu, Xuemin
Publicado em 2008

The GxxxG Motif in the Transmembrane Domain of AβPP Plays an Essential Role in the Interaction of CTFβ with the γ-secretase Complex and the Formation of Amyloid-β

Por Mao, Guozhang, Tan, Jianxin, Cui, Mei-Zhen, Chui, Dehua, Xu, Xuemin
Publicado no J Alzheimers Dis (2009)

Residues at P2-P1 positions of ε- and ζ-cleavage sites are important in formation of beta-amyloid peptide

Por Tan, Jianxin, Mao, Guozhang, Cui, Mei-Zhen, Lamb, Bruce, Sy, Man-Sun, Xu, Xuemin
Publicado em 2009

Death Receptor 6 Induces Apoptosis Not through Type I or Type II Pathways, but via a Unique Mitochondria-dependent Pathway by Interacting with Bax Protein

Por Zeng, Linlin, Li, Ting, Xu, Derek C., Liu, Jennifer, Mao, Guozhang, Cui, Mei-Zhen, Fu, Xueqi, Xu, Xuemin
Publicado em 2012

Effects of γ-secretase cleavage-region mutations on APP processing and Aβ formation: interpretation with sequential cleavage and α-helical model

Por Tan, Jianxin, Mao, Guozhang, Cui, Mei-Zhen, Kang, Shin-Chung, Lamb, Bruce, Wong, Boon-Seng, Sy, Man-Sun, Xu, Xuemin
Publicado no J Neurochem (2008)