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NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease

Ectopic cell cycle events (CCEs) mark vulnerable neuronal populations in human Alzheimer disease (AD) and are observed early in disease progression. In transgenic mouse models of AD, CCEs are found before the onset of β-amyloid peptide (Aβ) deposition to form senile plaques, a hallmark of AD. Here,...

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Bibliografski detalji
Glavni autori: Varvel, Nicholas H., Bhaskar, Kiran, Kounnas, Maria Z., Wagner, Steven L., Yang, Yan, Lamb, Bruce T., Herrup, Karl
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786797/
https://ncbi.nlm.nih.gov/pubmed/19907078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39716
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