Ectopic Cell Cycle Events Link Human Alzheimer's Disease and Amyloid Precursor Protein Transgenic Mouse Models

Nerve cells that re-enter a cell cycle will die rather than divide, a fact that likely underlies the neurodegeneration in Alzheimer's disease (AD). Several mouse models of familial AD have been created, and although many display amyloid plaques in their brains, none captures the extensive patte...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Yang, Yan, Varvel, Nicholas H., Lamb, Bruce T., Herrup, Karl
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
Subjects:
Neurobiology of Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675370/
https://ncbi.nlm.nih.gov/pubmed/16421297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3707-05.2006
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