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Ectopic Cell Cycle Events Link Human Alzheimer's Disease and Amyloid Precursor Protein Transgenic Mouse Models

Nerve cells that re-enter a cell cycle will die rather than divide, a fact that likely underlies the neurodegeneration in Alzheimer's disease (AD). Several mouse models of familial AD have been created, and although many display amyloid plaques in their brains, none captures the extensive patte...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yang, Yan, Varvel, Nicholas H., Lamb, Bruce T., Herrup, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675370/
https://ncbi.nlm.nih.gov/pubmed/16421297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3707-05.2006
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