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Ectopic Cell Cycle Events Link Human Alzheimer's Disease and Amyloid Precursor Protein Transgenic Mouse Models

Nerve cells that re-enter a cell cycle will die rather than divide, a fact that likely underlies the neurodegeneration in Alzheimer's disease (AD). Several mouse models of familial AD have been created, and although many display amyloid plaques in their brains, none captures the extensive patte...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Yang, Yan, Varvel, Nicholas H., Lamb, Bruce T., Herrup, Karl
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675370/
https://ncbi.nlm.nih.gov/pubmed/16421297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3707-05.2006
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