Microglial Derived Tumor Necrosis Factor-α Drives Alzheimer’s Disease-Related Neuronal Cell Cycle Events

Massive neuronal loss is a key pathological hallmark of Alzheimer’s disease (AD). However, the mechanisms are still unclear. Here we demonstrate that neuroinflammation, cell autonomous to microglia, is capable of inducing neuronal cell cycle events (CCEs), which are toxic for terminally differentiat...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhaskar, Kiran, Maphis, Nicole, Xu, Guixiang, Varvel, Nicholas H., Kokiko-Cochran, Olga N, Weick, Jason P., Staugaitis, Susan M., Cardona, Astrid, Ransohoff, Richard M., Herrup, Karl, Lamb, Bruce T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877710/
https://ncbi.nlm.nih.gov/pubmed/24141019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.10.007
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