Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology

Por Maphis, Nicole M., Jiang, Shanya, Binder, Jessica, Wright, Carrie, Gopalan, Banu, Lamb, Bruce T., Bhaskar, Kiran
Publicado no Front Mol Neurosci (2017)

Loss of tau rescues inflammation-mediated neurodegeneration

Por Maphis, Nicole, Xu, Guixiang, Kokiko-Cochran, Olga N., Cardona, Astrid E., Ransohoff, Richard M., Lamb, Bruce T., Bhaskar, Kiran
Publicado no Front Neurosci (2015)

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

Por Maphis, Nicole, Xu, Guixiang, Kokiko-Cochran, Olga N., Jiang, Shanya, Cardona, Astrid, Ransohoff, Richard M., Lamb, Bruce T., Bhaskar, Kiran
Publicado no Brain (2015)

Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology

Por Maphis, Nicole, Jiang, Shanya, Xu, Guixiang, Kokiko-Cochran, Olga N., Roy, Saktimayee M., Van Eldik, Linda J., Watterson, D. Martin, Lamb, Bruce T., Bhaskar, Kiran
Publicado no Alzheimers Res Ther (2016)

Microglial Derived Tumor Necrosis Factor-α Drives Alzheimer’s Disease-Related Neuronal Cell Cycle Events

Por Bhaskar, Kiran, Maphis, Nicole, Xu, Guixiang, Varvel, Nicholas H., Kokiko-Cochran, Olga N, Weick, Jason P., Staugaitis, Susan M., Cardona, Astrid, Ransohoff, Richard M., Herrup, Karl, Lamb, Bruce T.
Publicado em 2013

Photoreceptor Degeneration, Azoospermia, Leukoencephalopathy, and Abnormal RPE Cell Function in Mice Expressing an Early Stop Mutation in CLCN2

Por Edwards, Malia M., de Evsikova, Caralina Marín, Collin, Gayle B., Gifford, Elaine, Wu, Jiang, Hicks, Wanda L., Whiting, Carrie, Varvel, Nicholas H., Maphis, Nicole, Lamb, Bruce T., Naggert, Jürgen K., Nishina, Patsy M., Peachey, Neal S.
Publicado em 2010

Hypoxia promotes tau hyperphosphorylation with associated neuropathology in vascular dysfunction

Por Raz, Limor, Bhaskar, Kiran, Weaver, John, Marini, Sandro, Zhang, Quanguang, Thompson, Jeffery F., Espinoza, Candice, Iqbal, Sulaiman, Maphis, Nicole M., Weston, Lea, Sillerud, Laurel O., Caprihan, Arvind, Pesko, John C., Erhardt, Erik B., Rosenberg, Gary A.
Publicado no Neurobiol Dis (2018)

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential

Por Chauhan, Santosh, Ahmed, Zahra, Bradfute, Steven B., Arko-Mensah, John, Mandell, Michael A., Won Choi, Seong, Kimura, Tomonori, Blanchet, Fabien, Waller, Anna, Mudd, Michal H., Jiang, Shanya, Sklar, Larry, Timmins, Graham S., Maphis, Nicole, Bhaskar, Kiran, Piguet, Vincent, Deretic, Vojo
Publicado no Nat Commun (2015)

Genetically enhancing the expression of chemokine domain of CX(3)CL1 fails to prevent tau pathology in mouse models of tauopathy

Por Bemiller, Shane M., Maphis, Nicole M., Formica, Shane V., Wilson, Gina N., Miller, Crystal M., Xu, Guixiang, Kokiko-Cochran, Olga N., Kim, Ki-Wook, Jung, Steffen, Cannon, Judy L., Crish, Samuel D., Cardona, Astrid E., Lamb, Bruce T., Bhaskar, Kiran
Publicado no J Neuroinflammation (2018)

Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy

Por Maphis, Nicole M., Peabody, Julianne, Crossey, Erin, Jiang, Shanya, Jamaleddin Ahmad, Fadi A., Alvarez, Maria, Mansoor, Soiba Khalid, Yaney, Amanda, Yang, Yirong, Sillerud, Laurel O., Wilson, Colin M., Selwyn, Reed, Brigman, Jonathan L., Cannon, Judy L., Peabody, David S., Chackerian, Bryce, Bhaskar, Kiran
Publicado no NPJ Vaccines (2019)