Redox Regulation of Multidrug Resistance in Cancer Chemotherapy: Molecular Mechanisms and Therapeutic Opportunities

Por Kuo, Macus Tien
Publicado em 2009

Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy

Por Chen, Helen H. W., Kuo, Macus Tien
Publicado em 2010

Overcoming Platinum Drug Resistance with Copper-lowering Agents

Por CHEN, HELEN H.W., KUO, MACUS TIEN
Publicado em 2013

C‐Jun N‐terminal kinase signalling pathway in response to cisplatin

Por Yan, Dong, An, GuangYu, Kuo, Macus Tien
Publicado no J Cell Mol Med (2016)

Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes

Por Kuo, Macus Tien, Savaraj, Niramol, Feun, Lynn G.
Publicado em 2010

Gas6/Axl in arginine-starvation therapy

Por Tsai, Wen-Bin, Long, Yan, Kuo, Macus Tien
Publicado no Oncoscience (2015)

Role of the Human High-Affinity Copper Transporter (hCtr1) in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

Por Kuo, Macus Tien, Fu, Siqing, Savaraj, Niramol, Chen, Helen H. W.
Publicado em 2012

Overcoming Platinum Resistance through the Use of a Copper-Lowering Agent

Por Fu, Siqing, Naing, Aung, Fu, Caroline, Kuo, Macus Tien, Kurzrock, Razelle
Publicado em 2012

Effects of Cu(II) and cisplatin on the stability of Specific protein 1 (Sp1)-DNA binding: Insights into the regulation of copper homeostasis and platinum drug transport

Por Yan, Dong, Aiba, Isamu, Chen, Helen H W, Kuo, Macus Tien
Publicado no J Inorg Biochem (2016)

Specificity Protein 1 (Sp1) Oscillation Is Involved in Copper Homeostasis Maintenance by Regulating Human High-Affinity Copper Transporter 1 Expression

Por Liang, Zheng D., Tsai, Wen-Bin, Lee, Mei-Yi, Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2012

Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals

Por Liang, Zheng Dong, Long, Yan, Chen, Helen H. W., Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2013

Resistance to Arginine Deiminase Treatment in Melanoma Cells Is Associated with Induced Argininosuccinate Synthetase Expression involving c-Myc/HIF-1α/Sp4

Por Tsai, Wen-Bin, Aiba, Isamu, Lee, Soo-yong, Feun, Lynn, Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2009

p27(Kip1) as a prognostic factor in breast cancer: a systematic review and meta-analysis

Por Guan, Xiaoxiang, Wang, Yucai, Xie, Ruilian, Chen, Longbang, Bai, Jianling, Lu, Jia, Kuo, Macus Tien
Publicado em 2010

Activation of Ras/PI3K/ERK Pathway Induces c-Myc Stabilization to Upregulate Argininosuccinate Synthetase, Leading to Arginine Deiminase Resistance in Melanoma Cells

Por Tsai, Wen-Bin, Aiba, Isamu, Long, Yan, Lin, Hui-Kuan, Feun, Lynn, Savaraj, Niramol, Kuo, Macus Tien
Publicado em 2012

Arginine Deiminase Resistance in Melanoma Cells Is Associated with Metabolic Reprogramming, Glucose Dependence and Glutamine Addiction

Por Long, Yan, Tsai, Wen-Bin, Wangpaichitr, Medhi, Tsukamoto, Takashi, Savaraj, Niramol, Feun, Lynn G., Kuo, Macus Tien
Publicado em 2013

Transcription Factor Sp1 Plays an Important Role in the Regulation of Copper Homeostasis in Mammalian Cells

Por Song, Im-Sook, Chen, Helen H. W., Aiba, Isamu, Hossain, Anwar, Liang, Zheng D., Klomp, Leo W. J., Kuo, Macus Tien
Publicado em 2008

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin

Por Savaraj, Niramol, Wu, Chunjing, Li, Ying-Ying, Wangpaichitr, Medhi, You, Min, Bomalaski, John, He, Wei, Kuo, Macus Tien, Feun, Lynn G.
Publicado no Oncotarget (2015)

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is ind...

Por Long, Yan, Tsai, Wen-Bin, Chang, Jeffrey T., Estecio, Marcos, Wangpaichitr, Medhi, Savaraj, Naramol, Feun, Lynn G., Chen, Helen H.W., Kuo, Macus Tien
Publicado no Oncotarget (2016)

Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy

Por Chen, Helen H.W., Yan, Jiang-Jou, Chen, Wen-Chung, Kuo, Macus Tien, Lai, Yu-Hsuan, Lai, Wu-Wei, Liu, Hsiao-Sheng, Su, Wu-Chou
Publicado em 2011

Gas6/Axl is the sensor of Arginine-Auxotrophic Response in Targeted Chemotherapy with Arginine-Depleting Agents

Por Tsai, Wen-Bin, Long, Yan, Park, Jeong-Ran, Chang, Jeffrey T., Liu, Hui, Rodriguez-Canales, Jaime, Savaraj, Niramol, Feun, Lynn G., Davies, Michael A., Wistuba, Ignacio I, Kuo, Macus Tien
Publicado no Oncogene (2015)