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Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy

Three mechanisms have been proposed for the role of glutathione (GSH) in regulating cisplatin (CDDP) sensitivities that affects its ultimate cell-killing ability: (i) GSH may serve as a cofactor in facilitating multidrug resistance protein 2- (MRP2-) mediated CDDP efflux in mammalian cells, since MR...

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Bibliografski detalji
Glavni autori: Chen, Helen H. W., Kuo, Macus Tien
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946579/
https://ncbi.nlm.nih.gov/pubmed/20885916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/430939
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