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Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy
Three mechanisms have been proposed for the role of glutathione (GSH) in regulating cisplatin (CDDP) sensitivities that affects its ultimate cell-killing ability: (i) GSH may serve as a cofactor in facilitating multidrug resistance protein 2- (MRP2-) mediated CDDP efflux in mammalian cells, since MR...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946579/ https://ncbi.nlm.nih.gov/pubmed/20885916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/430939 |
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