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Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer Chemotherapy

Three mechanisms have been proposed for the role of glutathione (GSH) in regulating cisplatin (CDDP) sensitivities that affects its ultimate cell-killing ability: (i) GSH may serve as a cofactor in facilitating multidrug resistance protein 2- (MRP2-) mediated CDDP efflux in mammalian cells, since MR...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Helen H. W., Kuo, Macus Tien
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946579/
https://ncbi.nlm.nih.gov/pubmed/20885916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/430939
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