Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes

nork Kuo, Macus Tien, Savaraj, Niramol, Feun, Lynn G.
Argitaratua 2010

Targeting the Proline–Glutamine–Asparagine–Arginine Metabolic Axis in Amino Acid Starvation Cancer Therapy

nork Kuo, Macus Tien, Chen, Helen H. W., Feun, Lynn G., Savaraj, Niramol
Argitaratua izan da Pharmaceuticals (Basel) (2021)

Prolonged Complete Response With Combined Dabrafenib and Trametinib After BRAF Inhibitor Failure in BRAF-Mutant Glioblastoma

nork Kushnirsky, Marina, Feun, Lynn G., Gultekin, Sakir H., de la Fuente, Macarena I.
Argitaratua izan da JCO Precis Oncol (2020)

Arginine deprivation therapy for malignant melanoma

nork Yoon, Jung-Ki, Frankel, Arthur E, Feun, Lynn G, Ekmekcioglu, Suhendan, Kim, Kevin B
Argitaratua 2012

The Relationship of Thioredoxin-1 and Cisplatin Resistance: Its Impact on ROS and Oxidative Metabolism in Lung Cancer Cells

nork Wangpaichitr, Medhi, Theodoropoulos, George, Wu, Chunjing, You, Min, Feun, Lynn G., Kuo, Macus T., Savaraj, Niramol
Argitaratua 2012

N′(1),N′(3)-Dimethyl-N′(1),N′(3)-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (R...

nork Wangpaichitr, Medhi, Wu, Chunjing, You, Min, Maher, Johnathan C., Dinh, Vy, Feun, Lynn G., Savaraj, Niramol
Argitaratua 2009

Procollagen-Like Protein as a Molecular Target in the Treatment of Primary Brain Tumor

nork Wangpaichitr, Medhi, Landy, Howard, Wu, Chun Jing, Feun, Lynn G., Xu, Rong, Xu, Jenny, Savaraj, Niramol
Argitaratua izan da ScientificWorldJournal (2002)

Arginine Deiminase Resistance in Melanoma Cells Is Associated with Metabolic Reprogramming, Glucose Dependence and Glutamine Addiction

nork Long, Yan, Tsai, Wen-Bin, Wangpaichitr, Medhi, Tsukamoto, Takashi, Savaraj, Niramol, Feun, Lynn G., Kuo, Macus Tien
Argitaratua 2013

Phase II trial of SOM230 (pasireotide LAR) in patients with unresectable hepatocellular carcinoma

nork Feun, Lynn G, Wangpaichitr, Medhi, Li, Ying-Ying, Kwon, Deukwoo, Richman, Stephen P, Hosein, Peter J, Savaraj, Niramol
Argitaratua izan da J Hepatocell Carcinoma (2018)

Cisplatin Resistance and Redox-Metabolic Vulnerability: A Second Alteration

nork Wangpaichitr, Medhi, Theodoropoulos, George, Nguyen, Dan J. M., Wu, Chunjing, Spector, Sydney A., Feun, Lynn G., Savaraj, Niramol
Argitaratua izan da Int J Mol Sci (2021)

Enhancing the Effect of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Signaling and Arginine Deprivation in Melanoma

nork Wu, Chunjing, You, Min, Nguyen, Dao, Wangpaichitr, Medhi, Li, Ying-Ying, Feun, Lynn G., Kuo, Macus T., Savaraj, Niramol
Argitaratua izan da Int J Mol Sci (2021)

Collaboration Between RSK-EphA2 and Gas6-Axl RTK Signaling in Arginine Starvation Response That Confers Resistance to EGFR Inhibitors

nork Kuo, Macus Tien, Long, Yan, Tsai, Wen-Bin, Li, Ying-Ying, Chen, Helen H.W., Feun, Lynn G., Savaraj, Niramol
Argitaratua izan da Transl Oncol (2019)

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin

nork Savaraj, Niramol, Wu, Chunjing, Li, Ying-Ying, Wangpaichitr, Medhi, You, Min, Bomalaski, John, He, Wei, Kuo, Macus Tien, Feun, Lynn G.
Argitaratua izan da Oncotarget (2015)

Chromatin remodeling system p300-HDAC2-Sin3A is involved in Arginine Starvation-Induced HIF-1α Degradation at the ASS1 promoter for ASS1 Derepression

nork Tsai, Wen-Bin, Long, Yan, Chang, Jeffrey T., Savaraj, Niramol, Feun, Lynn G., Jung, Manfred, Chen, Helen H. W., Kuo, Macus Tien
Argitaratua izan da Sci Rep (2017)

Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer Therapy

nork Li, Ying-Ying, Feun, Lynn G., Thongkum, Angkana, Tu, Chiao-Hui, Chen, Shu-Mei, Wangpaichitr, Medhi, Wu, Chunjing, Kuo, Macus T., Savaraj, Niramol
Argitaratua izan da Int J Mol Sci (2017)

Targeting the kynurenine pathway for the treatment of cisplatin resistant lung cancer

nork Nguyen, Dan JM., Theodoropoulos, George, Li, Ying-Ying, Wu, Chunjing, sha, Wei, Feun, Lynn G., Lampidis, Theodore J., Savaraj, Niramol, Wangpaichitr, Medhi
Argitaratua izan da Mol Cancer Res (2019)

BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma

nork Li, Ying-Ying, Wu, Chunjing, Chen, Shu-Mei, Shah, Sumedh S., Wangpaichitr, Medhi, Feun, Lynn G., Kuo, Macus T., Suarez, Miguel, Prince, Jeffrey, Savaraj, Niramol
Argitaratua izan da Oncotarget (2016)

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is ind...

nork Long, Yan, Tsai, Wen-Bin, Chang, Jeffrey T., Estecio, Marcos, Wangpaichitr, Medhi, Savaraj, Naramol, Feun, Lynn G., Chen, Helen H.W., Kuo, Macus Tien
Argitaratua izan da Oncotarget (2016)

Degradation of AMPK‐α1 sensitizes BRAF inhibitor‐resistant melanoma cells to arginine deprivation

nork Li, Ying‐Ying, Wu, Chunjing, Shah, Sumedh S., Chen, Shu‐Mei, Wangpaichitr, Medhi, Kuo, Macus T., Feun, Lynn G., Han, Xiaoqing, Suarez, Miguel, Prince, Jeffrey, Savaraj, Niramol
Argitaratua izan da Mol Oncol (2017)

Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer

nork Wangpaichitr, Medhi, Wu, Chunjing, Li, Ying Ying, Nguyen, Dan J.M., Kandemir, Hande, Shah, Sumedh, Chen, Shumei, Feun, Lynn G., Prince, Jeffrey S., Kuo, Macus T., Savaraj, Niramol
Argitaratua izan da Oncotarget (2017)