Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes

Por Kuo, Macus Tien, Savaraj, Niramol, Feun, Lynn G.
Publicado em 2010

Arginine deprivation therapy for malignant melanoma

Por Yoon, Jung-Ki, Frankel, Arthur E, Feun, Lynn G, Ekmekcioglu, Suhendan, Kim, Kevin B
Publicado em 2012

The Relationship of Thioredoxin-1 and Cisplatin Resistance: Its Impact on ROS and Oxidative Metabolism in Lung Cancer Cells

Por Wangpaichitr, Medhi, Theodoropoulos, George, Wu, Chunjing, You, Min, Feun, Lynn G., Kuo, Macus T., Savaraj, Niramol
Publicado em 2012

N′(1),N′(3)-Dimethyl-N′(1),N′(3)-bis(phenylcarbonothioyl) Propanedihydrazide (Elesclomol) Selectively Kills Cisplatin Resistant Lung Cancer Cells through Reactive Oxygen Species (R...

Por Wangpaichitr, Medhi, Wu, Chunjing, You, Min, Maher, Johnathan C., Dinh, Vy, Feun, Lynn G., Savaraj, Niramol
Publicado em 2009

Arginine Deiminase Resistance in Melanoma Cells Is Associated with Metabolic Reprogramming, Glucose Dependence and Glutamine Addiction

Por Long, Yan, Tsai, Wen-Bin, Wangpaichitr, Medhi, Tsukamoto, Takashi, Savaraj, Niramol, Feun, Lynn G., Kuo, Macus Tien
Publicado em 2013

Targeting argininosuccinate synthetase negative melanomas using combination of arginine degrading enzyme and cisplatin

Por Savaraj, Niramol, Wu, Chunjing, Li, Ying-Ying, Wangpaichitr, Medhi, You, Min, Bomalaski, John, He, Wei, Kuo, Macus Tien, Feun, Lynn G.
Publicado no Oncotarget (2015)

BRAF inhibitor resistance enhances vulnerability to arginine deprivation in melanoma

Por Li, Ying-Ying, Wu, Chunjing, Chen, Shu-Mei, Shah, Sumedh S., Wangpaichitr, Medhi, Feun, Lynn G., Kuo, Macus T., Suarez, Miguel, Prince, Jeffrey, Savaraj, Niramol
Publicado no Oncotarget (2016)

Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is ind...

Por Long, Yan, Tsai, Wen-Bin, Chang, Jeffrey T., Estecio, Marcos, Wangpaichitr, Medhi, Savaraj, Naramol, Feun, Lynn G., Chen, Helen H.W., Kuo, Macus Tien
Publicado no Oncotarget (2016)

Gas6/Axl is the sensor of Arginine-Auxotrophic Response in Targeted Chemotherapy with Arginine-Depleting Agents

Por Tsai, Wen-Bin, Long, Yan, Park, Jeong-Ran, Chang, Jeffrey T., Liu, Hui, Rodriguez-Canales, Jaime, Savaraj, Niramol, Feun, Lynn G., Davies, Michael A., Wistuba, Ignacio I, Kuo, Macus Tien
Publicado no Oncogene (2015)

Targeting drug transport mechanisms for improving platinum-based cancer chemotherapy

Por Chen, Helen HW, Chen, Wen-Chung, Liang, Zhang-Dong, Tsai, Wen-Bin, Long, Yan, Aiba, Isamu, Fu, Siqing, Broaddus, Russell, Liu, Jinsong, Feun, Lynn G, Savaraj, Niramol, Kuo, Macus Tien
Publicado no Expert Opin Ther Targets (2015)

Double-Blind Phase III Randomized Trial of the Antiprogestin Agent Mifepristone in the Treatment of Unresectable Meningioma: SWOG S9005

Por Ji, Yongli, Rankin, Cathryn, Grunberg, Steven, Sherrod, Andy E., Ahmadi, Jamshid, Townsend, Jeannette J., Feun, Lynn G., Fredericks, Ruth K., Russell, Christy A., Kabbinavar, Fairooz F., Stelzer, Keith J., Schott, Anne, Verschraegen, Claire
Publicado no J Clin Oncol (2015)