Degradation of AMPK‐α1 sensitizes BRAF inhibitor‐resistant melanoma cells to arginine deprivation

Melanomas harboring BRAF mutation (V600E) are known to recur frequently following treatment with BRAF inhibitors (BRAFi) despite a high initial response rate. Our previous study has uncovered that BRAFi‐resistant melanoma (BR) cells are vulnerable to arginine deprivation. It has been reported that n...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Li, Ying‐Ying, Wu, Chunjing, Shah, Sumedh S., Chen, Shu‐Mei, Wangpaichitr, Medhi, Kuo, Macus T., Feun, Lynn G., Han, Xiaoqing, Suarez, Miguel, Prince, Jeffrey, Savaraj, Niramol
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709618/
https://ncbi.nlm.nih.gov/pubmed/29094484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12151
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